Defined Engineered Human Myocardium With Advanced Maturation for Applications in Heart Failure Modeling and Repair
نویسندگان
چکیده
منابع مشابه
Terminal differentiation, advanced organotypic maturation, and modeling of hypertrophic growth in engineered heart tissue.
RATIONALE Cardiac tissue engineering should provide "realistic" in vitro heart muscle models and surrogate tissue for myocardial repair. For either application, engineered myocardium should display features of native myocardium, including terminal differentiation, organotypic maturation, and hypertrophic growth. OBJECTIVE To test the hypothesis that 3D-engineered heart tissue (EHT) culture su...
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ژورنال
عنوان ژورنال: Circulation
سال: 2017
ISSN: 0009-7322,1524-4539
DOI: 10.1161/circulationaha.116.024145